A study suggests a new approach that might help treat Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis: making people's cells better at killing Mtb by harnessing RNA sensors in our cells, which detect the RNA of invading pathogens. For the first time, researchers have shown that RNA sensing is important in inhibiting Mtb's growth once it gets inside cells.

With a shortage of new tuberculosis drugs in the pipeline, a software tool can predict how current drugs--including unlikely candidates -- can be combined in new ways to create more effective treatments.

Each year, more and more people are getting mycobacterial lung infections, and the total number living with such diseases is going up, according to a new study published in the journal Annals of the American Thoracic Society. Those at greatest risk are people above the age of 65 years and the elderly.

Chronic transplant rejection can be deadly, and recognising it as early as possible is key to achieving the best possible patient outcomes.

The world is sorely in need of new ways to prevent TB, not just treat it. Drugs to stave off the infection do exist, but the months-long regimens are difficult and people often do not finish the prescribed courses.